Webb Therapy Uncategorized What Alcohol does to the Human Body

What Alcohol does to the Human Body

1. Alcohol (ethanol) enters the body through the oral cavity (i.e., the mouth). The inner surface of the oral cavity is mucosal tissue to keep the cavity lubricated and it is capable of absorbing alcohol into the bloodstream. This absorption is considered “insignificant”.

2. Alcohol flows down the oesophagus to the stomach where 10-20% of ethanol will be absorbed into the bloodstream. Alcohol enters the bloodstream via the mucosal tissue of the stomach wall, and travels straight to the liver. Alcohol can take 5-10 minutes to reach the brain because of the ethanol absorbed via the stomach. If you drink alcohol on an empty stomach, the pyloric sphincter [gateway between the stomach and the small intestine] is going to be more open, and the alcohol is going to immediately enter the small intestine after reaching the stomach. If food is also present in the stomach, the sphincter will open and close at a rate that allows food to enter the small intestine gradually, therefore if alcohol is also in the stomach, it will gradually enter the small intestine.

3. Alcohol flows through the pyloric sphincter into the small intestines where most alcohol absorption occurs. Human intestines are attached the to the posterior abdominal wall by a fold of membrane called the mesentery. Alcohol is absorbed into the mesentery via veins and then travels to the liver.

4. One function of the liver is that it detoxifies toxic elements into non-toxic elements before passing it to the heart and then the rest of the body. The liver sustains considerable “abuse” from a variety of toxic elements and chemicals, and therefore it needs to be capable of full regeneration. NOTE: Many diseases and exposures can harm it beyond the point of repair. These include cancer, hepatitis, certain medication overdoses, and fatty liver disease.

In the liver, ethanol is met with an enzyme called alcohol dehydrogenase and converts ethanol into acetaldehyde [ass-eh-tal-de-hide]. This chemical is more toxic than ethanol, so the liver uses another enzyme to convert acetaldehyde into acetate, which is non-toxic to the human body. NOTE: the amount of alcohol consumed + the timeframe it is consumed [and a variety of other factors] will influence the ability of the liver to effectively convert acetaldehyde all the way into acetate. The liver can’t handle the entire workload effectively therefore ethanol (before being metabolised) will go straight from the liver to the bloodstream and make its way directly to the heart.

NOTE: Genetics will play a role! Certain people do not produce the liver enzymes in enough quantity to properly breakdown ethanol.

5. Blood leaves the liver through the hepatic veins. The hepatic veins carry blood to the inferior vena cava—the largest vein in the body—to the right side of the heart. The heart will beat and send the incoming blood to the lungs to oxygenate and expel carbon dioxide as we breath out. This is how ethanol can be on your breath. Inside the lungs, at the very end of the bronchioles, are hollow air sacs called alveoli where there is a gas exchange. Ethanol evaporates through capillaries into the air sacs and exhaled out of the body. Breathalysers can detect the quantity of ethanol in a person’s system based on the quantity of ethanol in our breath.

6. Not all the ethanol will expel from the body via the breath. The rest will flow back to the heart, with newly oxygenated blood, and then get pumped all the way up to the brain and around the body. NOTE: Ethanol is water soluble. It will be distributed to every cell in the body except bone and fatty tissue [some will enter fat cells but not easily]. Ethanol will interact with every other cell i.e., every organ, gland, nerve, muscle etc.

7. Ethanol will affect and compromise protein synthesis inside muscle tissue. Therefore, if you have been training at the gym, running, swimming etc., your muscles will not effectively be able to repair.

8. Once ethanol has reached the brain, it will cross the blood-brain barrier and begin to affect chemical messengers [neurotransmitters] in the grey matter of the brain. It affects serotonin, dopamine, gamma-amino-butyric-acid (aka GABA), glutamate, endorphins etc. The person will experience pleasure, euphoria, lowered inhibitions [related to dopamine], lowered cognitive ability (e.g., decision making/problem solving, emotion regulation) and lowered coordination and reflexes.

The more ethanol ingested, the more dopamine is secreted and communicated between neurons (i.e., nerve cells). One of dopamine’s functions is to make you feel pleasure or ‘rewarded’ for doing things that are good for humans, hence, from an evolutionary perspective, we are likely to do them again to help us thrive in our environment and social world. Dopamine is secreted when we:

  • eat healthy foods (but also recently developed processed foods that are high in sugar and salt)
  • exercise
  • achieve goals
  • be productive (e.g., finish a task like cleaning, cooking, work-related tasks)
  • master new skills (e.g., learning an instrument or a new talent), and
  • have positive and stimulating social interactions

Ethanol influences so much dopamine secretion and communication that the brain becomes unable to make responsible decisions cognitively. The simultaneous experience of euphoria and lowered cognitive ability means we are more likely to be “happy” about making irresponsible decisions.

Increased dopamine is how drinking alcohol “blocks” unpleasant emotions like fear, stress, anxiety, and insecurity. When we don’t feel these unpleasant, yet necessary, emotions we will behave in ways that are dangerous, abnormal, potentially embarrassing, and generally problematic.

Another significant brain region affected by ethanol is the hypothalamus and the pituitary glad [together known as the hypothalamic-pituitary axis]. These structures control the entire hormonal system. The hypothalamus monitors the body, and it will send instructions to the pituitary gland based on information it receives from the hypothalamus. The hypothalamus is aware that ethanol is flooding the brain and it starts adjusting the secretion of hormones via the pituitary gland.

One of the instructions it gives the pituitary gland is to start modulating the adrenal glands to secrete cortisol (i.e., stress hormone) and epinephrine and norepinephrine (i.e., adrenaline).

Now, our cognitive capacity is diminished, inhibitions are lowered, and we will experience a rush of stress hormones and adrenaline coursing through the body. Cortisol and adrenaline will provide a boost of energy. It will increase the heart rate, blood pressure, body sweat, sugar levels in the bloodstream, and enhances the brain’s ability to use glucose. Glucose is a “fuel” source for brain functioning, including the generation of neurotransmitters. Behaviourally, we can see this in children when we say they are “hyperactive” because they’ve ingested too much sugar.

The pituitary gland will also slow the secretion of anti-diuretic hormone (aka. vasopressin). A diuretic is something that makes us urinate. If the anti-diuretic hormone (also called vasopressin) slows down, then we won’t be “holding on” to water as effectively, hence we begin to urinate more. People call this “breaking the seal”.

9. South of the body, blood is pumped into the kidneys via the renal artery which spreads through the renal cortex. The blood is then filtered into urine and expelled from the body. The lowered anti-diuretic hormone will dilate (become wider/bigger or more open) blood vessels in the kidneys which means more blood gets passed through and filtered, but it also means we lose a lot more body water which leads to dehydration. Vasopressin is essential in the control of osmotic balance, blood pressure regulations, and kidney function, therefore, when vasopressin is lowered, we are losing essential water and minerals/electrolytes. Electrolytes are involved in urination because the kidneys need them to make the process of filtering blood more efficient.

The loss of water and electrolytes will contribute to a hangover. Electrolytes play a role in cellular water absorption so if we are losing more water than we are bringing in, and we are losing the electrolytes that support the absorption of water, we become dehydrated very quickly.

10. The Hangover

Symptoms: nausea, fatigue, diarrhoea, vomiting, paranoia, anxiety, anorexia (i.e., loss of appetite), increased thirst, muscle weakness, irritability, sweating, increased blood pressure, and headache.

The exact cause of a “hangover” is not yet known however variables affecting the hangover are:

  • individual differences such as sex, size, body fat, genetics etc
  • lack of sleep
  • general health
  • drinking behaviour e.g., frequency, duration, quantity
  • food intake before and during
  • water intake before and after
  • your body’s ability to metabolise alcohol i.e., excessive amounts of acetaldehyde due to fewer enzymes to metabolise alcohol in the liver before entering the bloodstream
  • general behaviour while drinking e.g., poly-substance use, dancing, sexual activity, risk-taking behaviours etc.

Strategies for Controlled Drinking

  • Setting personal drinking limits and sticking to it
  • Alternating alcoholic drinks with soft drinks i.e., one alcoholic drink then a water, soft drink, or juice
  • Have a meal before drinking
  • Switching to low alcohol drinks
  • Having regular alcohol-free days/weeks/months
  • Identifying high risk situations for heavy drinking and creating a management plan

Engaging in alternative activities to drinking

Related Post

What is your intention? Why “will power” is often not enough.What is your intention? Why “will power” is often not enough.

Adapted from AIPC (2022), Institute Inbrief, Issue 363.

Oftentimes, a brand new year is used like a clean slate. We can do this any time throughout the year, however, I understand that there is an added element of our “collective consciousness” in the universal atmosphere motivating us with some renewed energy and will. At this time of year, humans perceive that everyone else is also feeling hopeful, invigorated, and full of promise. But the road to realisation of goals is littered with the carcasses of broken dreams, unfulfilled promises, and intentions that dissipated in the stress and mundane of everyday life – our goals did not receive the “oxygen” required to be sustainable.

What is our “Will”?

Have you ever fallen short of accomplishing you New Year’s Resolution? Sometimes, even before the end of New Year’s Day? People many think, “I don’t have the will power to sustain it”, however, if we look at this from the perspective of Psychosynthesis, a transpersonal psychology, we will understand why our understanding of “will power” if often incorrect. If you did anything today, you have will inside you. You have drive, motive, and energy.

While our will may not have all the “power” that we would like it to have, our will is always present with us, somewhere. Psychosynthesis counsellors, especially trained to be observant about will, acknowledge that one of their sacred duties with clients is to track their will, but all mental health professionals can tune more into the willing function of self, for the ultimate good of the client. What do we need to know to do that?

First, will isn’t just desire energy. It is not synonymous with control, it is not about “strong-arming” someone, and it isn’t merely about repressing undesirable material.

Personal and transpersonal will

At a personal level, “will” can be understood as an essential impulse toward our own wholeness. It is that drive within us which coordinates the often-conflicting parts of our personalities into self-expression. As the function closest to the self, it regulates and directs other functions, such as imagination, intuition, impulses, sensations, thoughts, and feelings. It is will which guides us toward personal integration. As we align our lives with a broader vision for what we may be, we go beyond personal will, receiving guidance from transpersonal will: the will of Self (as opposed to “self”).

Along that journey, however, people can fail to execute our will in a way which allows our goals to be realised. This post looks at the aspects of will, which, if they are not employed or are employed badly, can stunt the client’s intentions, keeping their goals from ever realising.

Aspects of will: Strength, Skill, and Virtue


When people make statements as mentioned above, decrying their lack of “will power” or “internal energy”, they are probably referring to the most well-known aspect of will: that is, “strong will”. It is believed that when we are born, we are unaware that we are separate from our birth giver. The beginning of individuation (the process of forming a stable personality) is the beginning of recognising that “will” exists. We are not only separate from Mum; we actually want something other than what Mum seems to be giving us. We come to see that we have arms and legs and a mouth, so we use these tools to explore the world the way we want to. We learn that crying will have certain needs met. It is the aspect of “strong will” that ensures that our willed act — say, crying for food — contains enough intensity or “drive” to carry out its purpose (getting us fed).

In other words, have you ever seen a really hungry baby stop crying after a very short time if it is not fed? Generally, not. It is possible that our new diet or exercise regime has failed because we didn’t elicit the intensity or “drive” to the intention to exercise or stick to our new diet. We may need to explore what situations in life are keeping us from applying greater intensity to the question. Maybe our desire to change is not worth the requisite “will” or “energy”. The road of least resistance is very common as we age and accumulate more life responsibilities.

This is not true for everyone. Some people will vehemently proclaim that do want to change. It is not lack of wanting, or lack of “will”. What is missing may be the second aspect of “will”, equally important to the first: that of skilful will.


Several sayings are relevant here:

  1. Environment is stronger than will power.
  2. When imagination and will power go up against one another, imagination wins every time.

These axioms allude to the often-unrecognised reality that we cannot generally achieve our goals through strong will, alone. Consider the alcoholic who desperately wants to stop drinking but they continue relapsing. If we put our will into competition with other psychological forces — such as impulse or feeling — it becomes overwhelmed; we end up stressed without accomplishing our goal. What we are missing in this case is likely to be the capacity to develop strategy, approaching the goal skilfully, and practically. Oftentimes, we want to achieve our goal without attaining the skills necessary to achieve it.

If you want to lose weight, for example, could think that you simply need to eat fewer calories and the extra kilo’s will start dropping off. Calories in Vs Calories out. But your role as strategist can be very helpful if you establish, for example, whether you’re often in situations where controlling food intake is difficult: say, when going out to eat or eating at private parties, or it’s the holiday like Christmas. Are you eating balanced meals, with sufficient protein (for example) to sustain yourself? Are you getting enough sleep to avoid overproduction of the hunger-inducing hormone ghrelin? How much do you know about body composition, the endocrine system, metabolism, nutrition, and exercise physiology?

There are myriad ways to be skilful around weight loss plans, and you may need to consider adopting some of them for success. For example, do you have effective interpersonal skills to communicate your needs to the people in your life that exercise and healthy eating is valuable to you, and you need their support? Or do you have the skills to join a peer group that exercises regularly. Perhaps you could improve your financial skills to budget for a Personal Trainer.

If we must merely “strong-arm” ourselves to achieve every end, we end up exhausted and discouraged, with few accomplishments. “Skilful will” allows us to use will not as a direct power or force, but as a function which stimulates, regulates, and directs other functions of ourselves so that they lead to the goal. For example, learning mindful eating skills may cultivate a relationship with bodily sensations which allows you to observe the sensation of true hunger pains as opposed to times when you eat because of boredom or wanting to feel good (temporarily). You can also learn skills to meet alleviate boredom or feeling emotionally nourished in other ways.

Even with employing strong and skilful will, however, your may not achieve your goal(s). That’s okay. Please do not judge yourself. It’s what Buddhism called the second arrow. That is, you already didn’t meet your goal (the first arrow) and then you judge yourself for it (the second arrow). You are human, not superhuman.

A third aspect, equally important with the first two, may also need to be employed. It is “Virtuous Will”.


Is your goal something you can achieve all by yourself through prudent use of strong and skilful will? No one is an island; we all live in communities and interact with family, friends, co-workers, gym instructors, enemies, and others on a regular basis. Those willed acts that succeed in accomplishing the will-er’s goal do so because they have considered the need to choose goals that are consistent with the welfare of others and the common good of humanity. They also must be consistent with “virtuous will” to the “self”.

The bottom line here is that many people need to do serious work around having virtuous will for themselves. For example, if you “hate” yourself for weighing more than what you would like, the motivation for change is unlikely to succeed because it is born in self-hatred. It is more effective to improve your self-esteem and sense of worth as a person, independent of your goal, so that any weight loss and subsequent weight maintenance can be in the context of “something I do to value myself; I like myself as I am and want to enhance the health of that self”.

Accessing transpersonal will

According to Roberto Assagioli, the founder of Psychosynthesis, using our will doesn’t stop with developing strong, skilful, and virtuous will: the three aspects of personal will. Assagioli claims that we can manifest all three of those and still be unhappy if we do not see how our personal goals align with something greater than ourselves. Having that solid sense of meaning and purpose to achieve something beyond the benefit of our little “self” helps us to reach beyond the limitations of ordinary consciousness to more expanded, intense states of awareness.

To yearn for that and not have it is what Viktor Frankl called “the abyss experience”: the opposite of Maslow’s peak experience (Boeree, 2006). Yet it is often in the abyss and despair of meaninglessness that we feel the pull of the superconscious, activating our transpersonal will and giving us access to another level of being. And then life becomes more interesting, as we try to balance the needs of material life (our immanence) and those of our higher levels of being (our transcendence), experienced as intentions arising from our transpersonal will.

Even the hypothetical person’s goal of weight loss (seemingly a very personal goal) may be able to access transpersonal will. Let’s say you lose the weight, arriving at your goal weight. You may enjoy a slender new body for a while, but ultimately that may not be enough to sustain lasting contentment, peace, and satisfaction. Looking “good” may not be the sole purpose of the original intention. If you can transform your goal, however, to a goal more inclusive of potential good for humanity as a whole — you may find that your personal will is aligned with transpersonal will. Just look at all the people on Youtube trying to help others, or the reward and continued sobriety members of Alcoholics Anonymous are given by “helping others”. Transpersonal will goes beyond the self and comes back to support our intention. Perhaps you want to write about healthy-body image as a method to transcend your Will to others.

The Will and the End of this Article

An effective and intentional use of will increases joy, openheartedness, and equanimity. Through use of not only strong will, but also skilful and good will — and perhaps even transpersonal will — your New Year’s resolutions will be far more likely to succeed, and you can experience willing as an act that leads to joy.


  1. Assagioli, R. (1973/1984). The act of will: A guide to self-actualization and self-realization. Wellingborough: Turnstone Press.
  2. Boeree, C. G. (2006). Viktor Frankl. Personality theories. Shippensburg University. Retrieved on 5 November, 2012, from: Website.
  3. Mental Health Academy. (n.d.). Understanding Will. Mental Health Academy.

Toxic Shame and the Gifts of Healthy Shame.Toxic Shame and the Gifts of Healthy Shame.

Think about what it means to be human. Yes, we have internalised toxic levels of pressure to be a certain way. We also know, as we mature, that being a certain way it complete bull shit and nonsense. I saw a quote once that said  “Can you remember who you werebefore the world told you who you should be?” -Charles Bukowski. I don’t know who this person is, but it’s the truth. Come home to yourself, and reach out for help from a professional if you need some support or help with that.